Comparing Three Types of Specialist Pacemakers to Improve Heart Function and Reduce Rhythm Problems in Heart Failure
Recruiting
N/A
Interventional Study
Heart Failure and Reduced Ejection Fraction
Dyssynchrony
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 60 (estimated)
- Sponsor
- Imperial College London · Other
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About This Trial
The goal of this clinical trial is to find out which type of specialist pacemaker-known as cardiac resynchronisation therapy (CRT)-works best for people with heart failure and a delay in how the lower chambers of the heart beat together (called electrical dyssynchrony).
The main aims of the study are:
To compare the effects of conventional biventricular pacing (BVP), conduction system pacing (CS…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Patients referred/scheduled for a CRT procedure (new implant or upgrade) who have:
* Symptomatic heart failure (NYHA II-IV)
* Reduced ejection fraction (LVEF≤40%)
* Prolonged QRS duration (≥130ms) and left bundle branch block ECG morphology or very prolonged QRS duration (\>150…
Contacts