A Study to Learn About mRNA Vaccines Against Influenza in Adults
Recruiting
Phase 2Interventional Study
Healthy Adults
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Prevention
Participants needed
770 (estimated)
Sponsor
Pfizer · Industry
Who this trial is looking for
This trial is looking for healthy adults aged 18 and older to learn about a new flu vaccine. Participants will receive one dose of the vaccine and will be involved for about 6 months, with three study visits required.
Are You a Good Fit for This Trial?
You may be able to join if
I am at least 18 years old
I am healthy and medically stable
You may not be able to join if
I tested positive for influenza in the last 5 months
I received any flu vaccine in the last 5 months
I was given antiviral flu medications in the last 5 months
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The purpose of this study is to learn about safety in participants taking the study vaccine (mRNA-based vaccine) and the ability of the study vaccine to trigger the body's immune response, targeting the flu virus (influenza virus).
This study is seeking healthy participants 18 years of age or older. All participants in this study will receive only 1 dose in their arm, to deliver one of the experi…
The purpose of this study is to learn about safety in participants taking the study vaccine (mRNA-based vaccine) and the ability of the study vaccine to trigger the body's immune response, targeting the flu virus (influenza virus).
This study is seeking healthy participants 18 years of age or older. All participants in this study will receive only 1 dose in their arm, to deliver one of the experimental flu vaccines or one of the approved flu vaccines used for comparison.
Participants will take part in this study for about 6 months, and participants will need to visit the study site at least 3 times. A blood sample will be taken at each of the 3 planned study visits and a swab from inside the nose will be taken at the first study visit.
Trial Locations
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Eligibility Criteria
Inclusion Criteria
• Healthy and medically stable participants who are determined by medical history, physical examination (if clinically required), and clinical judgment of the investigator to be eligible for inclusion in the study.
Exclusion Criteria
* Tested positive for influenza ≤5 months (1…
Inclusion Criteria
• Healthy and medically stable participants who are determined by medical history, physical examination (if clinically required), and clinical judgment of the investigator to be eligible for inclusion in the study.
Exclusion Criteria
* Tested positive for influenza ≤5 months (150 days) prior to Visit 1 (Day 1).
* Vaccination with any investigational or licensed influenza vaccine ≤5 months (150 days) before Visit 1 (Day 1).
* Receipt of antiviral therapies for influenza (eg, Tamiflu) ≤5 months (150 days) prior to Visit 1 (Day 1).
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