Impact of C-Mill Rehabilitation on the Gut-Brain Axis in Parkinson's Disease

Recruiting N/A Interventional Study
Parkinson Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
40 – 70
Sex
Any
Study type
Interventional
Purpose
Health Services Research
Participants needed
60 (estimated)
Sponsor
IRCCS Centro Neurolesi Bonino Pulejo · Other
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About This Trial
The GM-REHAB-2025 study aims to evaluate the impact of physiotherapy interventions using the C-Mill treadmill, with and without semi-immersive virtual reality, on gut microbiota and metabolic parameters in patients with Parkinson's disease. Three groups will be involved: one undergoing conventional physiotherapy, one treated with the C-Mill without virtual reality (VR), and one treated with C-Mill…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Diagnosis of PD according to the Movement Disorder Society Clinical * Diagnostic Criteria for Parkinson's Disease * Age comprised between 40 to 70 years * Patients with moderate to advanced disease (2 ≤ Hoehn and Yahr classification grade ≤ 4) * Individuals able to walk indepe…
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