EarLy Treatment Response in nEoVascular Macular Degeneration With Eylea 8mg: ELEV8 A Prospective Observational Open Label Study Investigating the Fluid Dynamics During Early Response to Aflibercept 8mg in Patients With Exudative Age-related Macular Degeneration (AMD).

Recruiting Observational Study
Age-Related Macular Degeneration (AMD)
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
50 and older
Sex
Any
Study type
Observational
Participants needed
50 (estimated)
Sponsor
Insel Gruppe AG, University Hospital Bern · Other
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About This Trial

This prospective, observational, open-label study evaluates early treatment response to intravitreal aflibercept 8 mg in patients with exudative age-related macular degeneration. Retinal fluid dynamics assessed by optical coherence tomography and changes in best-corrected visual acuity two months after baseline are analyzed to characterize early treatment outcomes.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Diagnosis of subfoveal CNV secondary to wAMD without restriction of lesion size. Active wAMD lesions are characterised by the following: * Evidence of SRF and/or IRF and * area of fibrosis less than 50% of the lesion area. BCVA scores at both screening and baseline must be 23 …
Contacts

Florian M Heussen, Dr. med.

+41 (0)31 664 54 24

florian.heussen@insel.ch

CONTACT

Martin S Zinkernagel, Prof. Dr. Dr. med.

+41 (0)31 632 85 03

martin.zinkernagel@insel.ch

CONTACT