A Clinical Trial in Healthy Participants to Learn How Itraconazole Affects MK-2828 Levels and How MK-2828 Affects Midazolam Levels (MK-2828-007)
Recruiting
Phase 1
Interventional Study
Healthy
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 24 – 60
- Sex
- Any
- Trial phase
- Phase 1
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 28 (estimated)
- Sponsor
- Merck Sharp & Dohme LLC · Industry
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About This Trial
The main goals of this study are:
* To learn what happens to one dose of MK-2828 in a healthy person's body over time when it is taken with itraconzole
* To learn what happens to one dose of midazolam in a healthy person's body over time when it is taken with MK-2828
Researchers want to learn if the levels of MK-2828 in the body are about the same when MK-2828 is taken with itraconazole as when …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
The main inclusion criteria include but are not limited to the following:
\- Participant is in good health
Exclusion Criteria:
The main exclusion criteria include but are not limited to the following:
* History of cancer (malignancy)
* History of clinically significant endoc…
Contacts