Blood Biomarkers for Alzheimer Disease and Neuro-injury to Estimate the Association With Cognitive/Functional Decline and Mortality in a Real-world Population of GERiatric Hospitalized Patients (BAD-GER)
Recruiting
Observational Study
Alzheimer DiseaseOld Age; Dementia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
65 and older
Sex
Any
Study type
Observational
Participants needed
400 (estimated)
Sponsor
Istituto Nazionale di Ricovero e Cura per Anziani · Other
Who this trial is looking for
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The BAD-GER study is a multicenter, prospective, three-arm observational study serving to validate a prognostic biomarker algorithm for mortality and hospital readmission; this algorithm will be developed through the retrospective analysis of Alzheimer's Disease and neurodegeneration biomarkers in an already available discovery cohort of 700 previously hospitalized geriatric patients.
Trial Locations
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Status
Eligibility Criteria
GROUP 1: Patients hospitalized for acute neurological disorders
Inclusion criteria:
* Inpatients with one of the following diagnoses: ischemic or hemorrhagic stroke, delirium, status epilepticus, encephalitis/meningitis
Exclusion criteria:
* no informed consent
GROUP 2: Patients hospitalized fo…
GROUP 1: Patients hospitalized for acute neurological disorders
Inclusion criteria:
* Inpatients with one of the following diagnoses: ischemic or hemorrhagic stroke, delirium, status epilepticus, encephalitis/meningitis
Exclusion criteria:
* no informed consent
GROUP 2: Patients hospitalized for non-neurological diseases with dementia
Inclusion criteria:
* inpatients with diagnosis of major neurocognitive disorder according to DSM-5 criteria (2013)
Exclusion criteria:
* Inpatients with one of the following diagnoses: ischemic or hemorrhagic stroke, delirium, status epilepticus, encephalitis/meningitis
* no informed consent
GROUP 3: Patients hospitalized for non-neurological diseases without dementia
Inclusion criteria:
* inpatients with non-neurological diseases
Exclusion criteria:
* inpatients with one of the following diagnoses: ischemic or hemorrhagic stroke, delirium, status epilepticus, encephalitis/meningitis
* diagnosis of dementia
* no informed consent
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