Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-272 in Healthy Participants

Recruiting Phase 1 Interventional Study
Cystic Fibrosis
Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 – 55
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
128 (estimated)
Sponsor
Vertex Pharmaceuticals Incorporated · Industry
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About This Trial

The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of single and multiple ascending doses of VX-272.

Trial Locations
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Eligibility Criteria
Key Inclusion Criteria: * Body mass index (BMI) of 18.0 to 32.0 kilogram per meter square (kg/m\^2) * A total body weight of more than (\>) 50 kg * Male and Female participants of non-childbearing potential Key Exclusion Criteria: * History of febrile illness or other acute illness that has not f…
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Medical Information

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medicalinfo@vrtx.com

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