Study on Nighttime Wakefulness and Suicidal Thoughts
Mind After Midnight
Recruiting
N/AInterventional Study
Suicidal IdeationCircadian Rhythm DisordersSleep DeprivationSleep Wake Disorders
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 55
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
90 (estimated)
Sponsor
University of Arizona · Other
Who this trial is looking for
This trial is looking for adults aged 18-55 with recent suicidal thoughts. Participants will be assessed about their mood and decision-making during night awakenings while experiencing different sleep pressures.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 18 and 55 years old
I have had suicidal thoughts in the past 6 months
I usually go to bed between 9:00 PM and 1:00 AM
I usually wake up between 6:00 AM and 9:00 AM
I can provide informed consent
You may not be able to join if
I have current suicidal thoughts that need immediate help
I have a primary sleep disorder
I have bipolar disorder or a psychotic disorder
I have a substance use disorder within the past 3 months
I take medications that significantly affect sleep
I work night shifts or have traveled across time zones in the past month
I have a medical or neurological condition that interferes with participation
I am pregnant
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This study examines whether wakefulness during the biological night (2:00-4:00 AM) is associated with increased negative mood, impaired decision-making, and suicidal thoughts. Adults with a history of suicidal ideation in the past six months will complete laboratory and home-based assessments under varying levels of sleep pressure. Participants will be evaluated during late-night wakefulness and u…
This study examines whether wakefulness during the biological night (2:00-4:00 AM) is associated with increased negative mood, impaired decision-making, and suicidal thoughts. Adults with a history of suicidal ideation in the past six months will complete laboratory and home-based assessments under varying levels of sleep pressure. Participants will be evaluated during late-night wakefulness and under conditions of both higher and lower sleep pressure. The goal of the study is to better understand the biological and behavioral mechanisms that may contribute to elevated suicide risk during nocturnal wakefulness.
Trial Locations
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Eligibility Criteria
Inclusion Criteria
* Age 18-55 years
* History of suicidal ideation within the past 6 months
* Habitual bedtime between 9:00 PM and 1:00 AM
* Habitual wake time between 6:00 AM and 9:00 AM
* Ability to provide informed consent
Exclusion Criteria:
* Current suicidal intent requiring immediate clin…
Inclusion Criteria
* Age 18-55 years
* History of suicidal ideation within the past 6 months
* Habitual bedtime between 9:00 PM and 1:00 AM
* Habitual wake time between 6:00 AM and 9:00 AM
* Ability to provide informed consent
Exclusion Criteria:
* Current suicidal intent requiring immediate clinical intervention
* Diagnosis of a primary sleep disorder (e.g., untreated obstructive sleep apnea, narcolepsy)
* Bipolar disorder or psychotic disorder
* Substance use disorder within the past 3 months
* Use of medications that significantly affect sleep or circadian rhythms
* Night shift work or transmeridian travel within the past month
* Medical or neurological condition that would interfere with participation
* Pregnancy
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