Perioperative Sepsis. An Epigenetic Perspective
Recruiting
Observational Study
Sepsis Abdominal
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 40 (estimated)
- Sponsor
- Carol Davila University of Medicine and Pharmacy · Other
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About This Trial
This single-center, prospective, observational study evaluates the impact of perioperative sepsis on inflammatory response, coagulation abnormalities, cardiac dysfunction, and microRNA expression in adult patients undergoing major abdominal surgery. Forty patients are enrolled and classified into septic and non-septic groups according to international sepsis definitions based on SOFA score criteri…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age ≥18 years
* Undergoing major abdominal surgery (elective or emergency)
* Ability to provide written informed consent
* Availability of biological samples in the preoperative period and within 24 hours postoperatively
* Preoperative hemodynamic stability
Exclusion Criteria…
Contacts