Effect of Dexmedetomidine Dosage on Postoperative Delirium in Geriatric Orthopedic Surgery
Recruiting
Phase 2
Interventional Study
Delirium - Postoperative
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 55 – 70
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 75 (estimated)
- Sponsor
- Benha University · Other
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About This Trial
This study evaluates the dose-response relationship of Dexmedetomidine (DEX) in reducing the incidence and severity of postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) in elderly patients. The study compares different doses of DEX against a fentanyl control group in patients undergoing major lower limb orthopedic surgery under general anesthesia to determine the optimal …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Elderly surgical patients.
* ASA physical status grade II-III.
* Planned major lower limb orthopedic surgery.
Exclusion Criteria:
* pre-existing dementia or drug allergies
Contacts