Transformative Research in Diabetic Nephropathy 2.0
Recruiting
Observational Study
Diabetic Nephropathies
Kidney Diseases
Renal Insufficiency, Chronic
Diabetes Mellitus, Type 2
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 200 (estimated)
- Sponsor
- University of Pennsylvania · Other
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About This Trial
The goal of this observational study is to learn more about kidney health in adults with diabetic kidney disease and other groups. Researchers will study kidney tissue and other samples. They want to learn how sodium-glucose cotransporter-2 (SGLT2) inhibitors, a type of diabetes medicine, may affect the kidneys. People can join only if they are already having a kidney biopsy or kidney surgery as p…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age ≥18 years
* eGFR ≥10 ml/min/1.73 m2 based on the 2021 race-free CKD-EPI equation13
* Underwent a clinically indicated kidney biopsy, living donor biopsy, or nephrectomy (non-tumor adjacent tissue available).
* Able and willing to provide informed consent for release of one…
Contacts