No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
60 and older
Sex
Any
Study type
Interventional
Purpose
Supportive Care
Participants needed
60 (estimated)
Sponsor
University of Pennsylvania · Other
Who this trial is looking for
This trial is looking for adults over 60 who are waiting for a kidney transplant. Participants will track their physical activity and join online exercise classes from home for 12 weeks.
Are You a Good Fit for This Trial?
You may be able to join if
I am at least 60 years old
I receive transplant care at Penn Medicine
I am on the kidney transplant waiting list
I speak and understand English
I can walk
I have at least one physical function limitation or frailty
I have internet access and can use an app
I can provide written consent and have medical clearance to exercise
You may not be able to join if
I have had a heart attack or stroke in the past 3 months
I cannot self-monitor with study devices
I have not been cleared to exercise
I am participating in another physical activity study
I have another reason that would prevent me from completing the study
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The goal of this clinical trial is to learn if a home-based exercise program can be safely and feasibly used to improve physical activity and physical function in adults waiting for a kidney transplant. The study will also learn how acceptable and useful this program is for participants.
The main questions it aims to answer are:
* Can a remote exercise program be delivered successfully to people…
The goal of this clinical trial is to learn if a home-based exercise program can be safely and feasibly used to improve physical activity and physical function in adults waiting for a kidney transplant. The study will also learn how acceptable and useful this program is for participants.
The main questions it aims to answer are:
* Can a remote exercise program be delivered successfully to people on the kidney transplant waiting list?
* Do participants follow the exercise program and wear a physical activity tracker as asked?
* Is the program safe and well tolerated?
Researchers will compare two groups to see if the exercise program leads to higher physical activity and better physical function:
* Usual pre-transplant care with a physical activity tracker
* Usual pre-transplant care plus an online exercise program
Participants will:
* Wear a wrist activity tracker to measure daily physical activity
* Complete a one-week baseline period before being assigned to a study group
* Be randomly assigned (like flipping a coin) to one of two groups
* If assigned to the exercise group, take part in online exercise classes at home for 12 weeks with reminders and feedback, and then another 12 weeks without reminders and feedback
* Answer questionnaires about their health, activity, and experience in the study
This study may help researchers learn how to better support people waiting for kidney transplant through safe, home-based exercise programs.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* be at least 60 years old
* receive transplant care at Penn Medicine
* be on the kidney transplant waiting list
* speak and comprehend English
* be able to walk
* have at least one physical function limitation OR at least one frailty metric
* have access to a device capable of …
Inclusion Criteria:
* be at least 60 years old
* receive transplant care at Penn Medicine
* be on the kidney transplant waiting list
* speak and comprehend English
* be able to walk
* have at least one physical function limitation OR at least one frailty metric
* have access to a device capable of connecting to the Internet and downloading an application
* be able to provide written informed consent
* be cleared for participant via the Physical Activity Readiness Questionnaire (PARQ) verified against medical record or via written medical clearance from a clinician
Exclusion Criteria:
* Have had a myocardial infarction or a stroke in the 3 months immediately prior to enrollment
* Be unable to self-monitor with study devices (i.e., have a condition such as dementia)
* Not cleared by PARQ or receive written medical clearance to exercise
* Participate in another physical activity study
* Have any other reason they do not expect to be able to complete the study
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