A Study of Guselkumab After Switching From Ustekinumab in Participants With Moderate to Severe Psoriasis
Recruiting
Observational Study
Psoriasis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
200 (estimated)
Sponsor
Janssen-Cilag Ltd. · Industry
Who this trial is looking for
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The purpose of this study is to assess the effectiveness and safety of guselkumab following a switch from ustekinumab or an ustekinumab biosimilar in participants with moderate to severe psoriasis, a chronic inflammatory skin disease characterized by erythematous, scaly plaques that may be associated with pain and pruritus, in routine clinical practice.
Trial Locations
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Status
Eligibility Criteria
Inclusion criteria:
* Must have a confirmed diagnosis of moderate-to-severe plaque psoriasis requiring systemic treatment
* Participants who are currently treated with Ustekinumab (either the originator or its biosimilar) and who are medically indicated to switch to Guselkumab
* Participants who, b…
Inclusion criteria:
* Must have a confirmed diagnosis of moderate-to-severe plaque psoriasis requiring systemic treatment
* Participants who are currently treated with Ustekinumab (either the originator or its biosimilar) and who are medically indicated to switch to Guselkumab
* Participants who, based on the Investigator's decision, should initiate treatment with Guselkumab
* Participants must understand and be willing and able to answer patient-reported outcomes (PROs)
* Must sign an informed consent form (ICF) allowing data collection and source data verification in accordance with local requirements
Exclusion criteria:
* Contraindication or hypersensitivity to Guselkumab or any ingredient in the injection solution/liquid
* Pregnancy or breastfeeding
* Currently enrolled in an interventional study
* Currently enrolled in an observational study sponsored or managed by a Janssen company
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