No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 65
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
10 (estimated)
Sponsor
Hospital Universitario Dr. Jose E. Gonzalez · Other
Who this trial is looking for
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In this study, researchers are looking to determine whether Gemcitabine/Oxaliplatin plus a lower dose of Epcoritamab (12 mg) works to treat subjects with relapsed/refractory diffuse large B-cell lymphoma, who are candidates to autologous stem cell transplantation.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Subjects with relapsed/refractory diffuse large B-cell lymphoma who have received at least 1 previous line of treatment and that are candidates to autologous stem cell transplant
* ECOG 0-2
* Women of reproductive age who agree on getting a contraceptive method
* Subjects who …
Inclusion Criteria:
* Subjects with relapsed/refractory diffuse large B-cell lymphoma who have received at least 1 previous line of treatment and that are candidates to autologous stem cell transplant
* ECOG 0-2
* Women of reproductive age who agree on getting a contraceptive method
* Subjects who fulfill Lugano´s criteria for disease activity
* Subjects who voluntarily accept to participate in this study
Exclusion Criteria:
* Active bacterial, viral or fungal infection
* Subjects who have already received an autologous o allogeneic stem cell transplantation
* Subjects with other active neoplasias
* Subjects with end-stage failure
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