Personalized Antiemetic Regimen According to Patients' Pharmacogenetic Profile

Recruiting Phase 2 Interventional Study
Breast Cancer
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 74
Sex
Female
Trial phase
Phase 2
Study type
Interventional
Purpose
Prevention
Participants needed
200 (estimated)
Sponsor
Chinese University of Hong Kong · Other
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About This Trial
The objectives of this study are to determine if pharmacogenetic (PG) analysis of an individual enable optimal selection of antiemetic regimen for patients undergoing the first cycle of AC (Adriamycin + Cyclophosphamide) or FEC (Fluorouracil + Epirubicin + Cyclophosphamide) chemotherapy. It also aims to compare the quality of life of patients in the first cycle of AC / FEC chemotherapy with and wi…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Chinese patient, female \>/=18 and \< 75 years of age. * Patient is diagnosed with early breast cancer. * Patient is naïve to emetogenic chemotherapy moderately or highly emetogenicity. * Patient is scheduled to receive her first course of neoadjuvant/adjuvant chemotherapy for…
Contacts

Winnie YEO, MBBS, MD, FRCP

3505 1042

winnie@clo.cuhk.edu.hk

CONTACT

Dong LAI, RN

3505 1138

dong@clo.cuhk.edu.hk

CONTACT