FET-PET/MRI for Pituitary Adenomas

Use of [18F] Fluoroethyl-L-tyrosine PET/MRI for Identifying Small Functional Pituitary Adenomas

Recruiting Phase 1 Interventional Study
Pituitary Adenoma
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 75
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Diagnostic
Participants needed
5 (estimated)
Sponsor
Mayo Clinic · Other
Who this trial is looking for

This trial is looking for adults aged 18 to 75 with certain types of pituitary tumors that are hard to see on regular MRIs. Participants will undergo special imaging to see if it helps in finding tumors and guiding treatment options.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am between 18 and 75 years old.
  • I have been diagnosed with Cushing's disease, Acromegaly, or tumor hyperprolactinemia.
  • My regular MRI results are not clear for identifying a tumor.
  • I am willing to have surgery if a tumor is found or I am already scheduled for surgery.
  • I can provide informed consent and complete the imaging tests.
  • I am a female of childbearing potential and have a negative pregnancy test within the last 48 hours.

You may not be able to join if

  • I cannot have MRI or PET scans.
  • I am allergic to contrast agents or other imaging materials.
  • I have severe medical issues that prevent me from participating.
  • My MRI clearly identified the adenoma.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial

The purpose of this research is to evaluate the diagnostic role and clinical efficacy of investigational FET-PET/MRI in detecting MRI-occult primary or residual/recurrent functional pituitary adenomas (PAs) and its influence on clinical and surgical decisions.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients 18 to 75 years of age with biochemically proven CD, Acromegaly, or tumor hyperprolactinemia as per current Endocrinology guidelines. * Clinical DCE-MRI protocol that is negative or equivocal for identifiable tumor. * Patient willing to have surgery if lesion found, or…
Contacts

Julia Santos

904-953-3280

santos.julia@mayo.edu

CONTACT