Aqueous Humor and Ocular Tissue Analysis in Glaucoma and Cataract
Recruiting
N/A
Interventional Study
Primary Open-Angle Glaucoma (POAG)
Cataract
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 40 (estimated)
- Sponsor
- Military Institute od Medicine National Research Institute · Other
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About This Trial
This observational study will compare proteomic and elemental profiles of aqueous humor and ocular tissues in patients with primary open-angle glaucoma (POAG) and cataract versus cataract controls without glaucoma. Samples collected during standard surgery will be analyzed using LC-MS/MS and ICP-MS. The goal is to identify glaucoma-associated molecular patterns with potential diagnostic or prognos…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age ≥ 18 years.
* Scheduled for cataract surgery (phacoemulsification with intraocular lens implantation).
* Ability to provide written informed consent.
* For glaucoma arm: diagnosis of primary open-angle glaucoma (POAG) with coexisting cataract, and planned combined cataract…
Contacts