Probiotic Improve Constipation

Inclusion Criteria: (1) Age 18-65 years; (2) Constipated patients (less than 3 bowel movements per week and/or Bristol Scale type 1 and 2); (3) Able to complete the study according to the trial protocol; (4) Patients who have signed the informed consent form; (5) Study participants (including male study participants) have no plans to have children within 14 days prior to screening and within 6 months after the end of the trial and voluntarily use effective contraception. \- Exclusion Criteria: 1. Those who have taken a substance with a similar function to the test subject in a short period of time, affecting their judgment of the results; 2. Patients who changed their diet during the study; 3. Patients with severe allergies and immunodeficiency; 4. Pregnant, breastfeeding, or women planning to become pregnant; 5. Those with severe diseases of vital organs such as the cardiovascular system, lungs, liver, and kidneys, diabetes, thyroid disease, severe metabolic diseases, malignant tumors, or severe immune system diseases; 6. Those who have used antibiotics in the past two weeks; 7. Those with severe psychological or mental illnesses; 8. Those who did not consume the test sample as required or did not follow up on time, resulting in the inability to determine the efficacy; 9. Other study participants deemed unsuitable by the researchers. -