Transcranial Doppler for Internal Carotid Artery Stenting (TCD-ICAS)

Recruiting N/A Interventional Study
Artery Stenosis
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
40 and older
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
232 (estimated)
Sponsor
General Hospital of Shenyang Military Region · Other
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About This Trial
Carotid artery stenting (CAS) prevents stroke but carries risks of perioperative cerebral embolism. Transcranial Doppler (TCD) ultrasound can detect microemboli during CAS and may offer therapeutic benefits through ultrasound-enhanced thrombolysis. Trials like SONOBUSTER and SONOBIRDIE suggest TCD reduces new brain infarctions during carotid procedures. The TCD-ICAS trial will investigate whether …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age ≥ 40 years old; * Patients with severe stenosis of the internal carotid artery; * Planned for carotid artery stent; * Modified Rankin Scale score ≤ 2; * The subject has adequate temporal bone windows to undergo TCD, and the blood flow signal of the middle cerebral artery i…
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