Advanced Brain Imaging-TKA (fMRI-TKA)

Recruiting N/A Interventional Study
Knee Osteoarthritis (Knee OA) Knee Pain Chronic Brain Network Connectivity Patient Satisfaction Brain MRI
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
50 (estimated)
Sponsor
Ottawa Hospital Research Institute · Other
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About This Trial
Knee replacement surgery is a common and effective treatment for pain and mobility loss, yet up to 1 in 5 patients remain dissatisfied after surgery due to ongoing pain or difficulty with daily activities. Currently, clinicians cannot reliably predict which patients will experience these challenges. This study uses MRI scan of the brain to investigate whether specific patterns of brain activity c…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Male and female patients aged 18 years or older 2. Primary TKA 3. Diagnosis of osteoarthritis, inflammatory arthritis, or osteonecrosis Exclusion Criteria: 1. Inability or refusal to sign informed consent form 2. Non-English or French speaking, and no licensed translator, f…
Contacts

Sanjula Costa

613-737-8899

scosta@ohri.ca

CONTACT