Small Bowel Capsule Endoscopy in Lynch Syndrome
Recruiting
Observational Study
MMR Mutation
Small Bowel Adenoma
Small-bowel Adenocarcinoma
Lynch Syndrome
Cancer
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 400 (estimated)
- Sponsor
- Assistance Publique - Hôpitaux de Paris · Other
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About This Trial
The impact of small bowel (SB) capsule endoscopy (CE) on the screening (followed by diagnosis and treatment) of (pre)neoplastic lesions of the small bowel in Lynch syndrome (LS) patients is unknown.
The iCARE4Lynch study is a retrospective cohort of patients carrying a pathogenic variant of the DNA mismatch repair gene (MMR) (MLH1, MSH2, MSH6, PMS2, EPCAM) who had had at least one SBCE for screen…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patient carrying a pathogenic variant of the DNA mismatch repair gene (MMR) (MLH1, MSH2, MSH6, PMS2, EPCAM)
* Capsule endoscopy screening for (pre)neoplastic lesions of the small intestine
* No opposition to the reuse of healthcare data for research purposes
Exclusion Criteri…
Contacts