tVNS and Approach-Avoidance Behavior in Anhedonia and Anxiety

Recruiting N/A Interventional Study
Healthy Participants Anxiety Disorders (With High Anxiety Symptoms) Depressive Disorders (With High Anhedonia Symptoms) Comorbid Depression and Anxiety Disorder (With High Anhedonia and High Anxiety Symptoms)
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 – 40
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
104 (estimated)
Sponsor
Dr. Nils B. Kroemer · Other
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About This Trial
This study investigates if anhedonia and anxiety symptoms are associated with alterations in reinforcement learning, effort trade-offs for wins vs. punishments, and foraging behavior under threat. Moreover, it will investigate whether these processes can be influenced by a metabolic load and/or transcutaneous vagus nerve stimulation (tVNS). The project consists of (a) an online reinforcement learn…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * BMI between 18,5 and 30,0 kg/m2, * between 18 and 40 years of age, and * be able and willing to provide informed consent. Exclusion Criteria: * have a high risk of suicide, * have a lifetime diagnosis of severe neurological disorder (incl. ADHD), schizophrenia, bipolar disor…
Contacts

Dr. Anne Kühnel

+49 228 28711519

akuehnel@uni-bonn.de

CONTACT