Radiotherapy After Prostatectomy for Node Positive Prostate Cancer

Recruiting Phase 3 Interventional Study
Prostate Cancer (Post Prostatectomy) Radiotherapy; Image-Guided Prostate Cancer Non-Metastatic Androgen Deprivation Therapy Lymph Node Positive
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Male
Trial phase
Phase 3
Study type
Interventional
Purpose
Treatment
Participants needed
372 (estimated)
Sponsor
Sun Yat-sen University · Other
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About This Trial
The goal of this clinical trial is to evaluate whether the addition of pelvic radiotherapy to androgen deprivation therapy (ADT) can delay disease progression and improve survival outcomes in patients with pathologically confirmed regional lymph node-positive (pN1) prostate cancer after radical prostatectomy. The main questions it aims to answer are: * Does ADT combined with pelvic radiotherapy …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 years. * Histologically confirmed adenocarcinoma of the prostate. * Radical prostatectomy with pelvic lymph node dissection and pathologically confirmed positive pelvic lymph nodes (AJCC 8th edition: external iliac, internal iliac, obturator, presacral, periprostatic,…
Contacts

Liru He, PhD

+862087343030

helir@sysucc.org.cn

CONTACT

Yang Liu, MD

+862087341521

liuyang1@sysucc.org.cn

CONTACT