Intranasal Dexmedetomidine-esketamine Administration and Postoperative Pain in Pediatric Patients
Recruiting
Phase 4
Interventional Study
Adenotonsillectomy
Children
Intranasal Administration
Dexmedetomidine
Esketamine
Postoperative Pain
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 3 – 7
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 160 (estimated)
- Sponsor
- Peking University First Hospital · Other
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About This Trial
Postoperative pain after adenoid and tonsil surgery is significant, with approximately 75% of pediatric patients experiencing severe postoperative pain. Currently, there is a lack of clinical strategies to safely and effectively manage postoperative pain in children undergoing adenoid and tonsil surgery. Dexmedetomidine and esketamine can achieve appropriate sedation levels and alleviate postopera…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Aged 3-7 years old.
* Scheduled to undergo adenoidectomy and/or tonsillectomy under general anesthesia.
* Provides written informed consent by the guardian.
Exclusion Criteria:
* Unsuitable for intranasal administration due to nasal diseases (such as rhinitis, nasal polyps, …
Contacts