Molecular Insights Into Post-Cardiac Arrest Brain Injury Via CSF Multi-Omics

Recruiting Observational Study
Cardiac Arrest (CA) Cerebrospinal Fluid Multiomics Hypoxic-Ischemic Brain Injury
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
60 (estimated)
Sponsor
Chungnam National University Hospital · Other
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About This Trial
The goal of this study is to uncover the molecular mechanisms responsible for secondary brain injury in patients with post-cardiac arrest syndrome by analyzing cerebrospinal fluid (CSF) using multi-omics techniques. The main question this study aims to answer is: Which genome-, transcriptome-, proteome-, and metabolome-level changes in CSF are associated with secondary brain injury after cardiac…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients receiving post-resuscitation care after out-of-hospital cardiac arrest for secondary brain injury treatment. * Patients without contraindications for lumbar puncture catheter insertion for cerebrospinal fluid (CSF) collection. This includes the absence of: * Uncontrol…
Contacts

Changshin Kang, MD. PhD

+821089928386

rosc@cnu.ac.kr

CONTACT