Methadone in the Management of Post-Operative Pain in Total Knee Replacement
Recruiting
Phase 4
Interventional Study
Total Knee Arthroplasty
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 21 – 75
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 192 (estimated)
- Sponsor
- AdventHealth · Other
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About This Trial
The goal of this study is to determine whether one dose of IV methadone given right before surgery will help patients' pain management after a total knee replacement and reduce the amount of pain medications taken in the weeks after surgery.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Provision of signed and dated informed consent from
2. Stated willingness to comply with all study procedures and availability to attend all required visits for the duration of the study.
3. Age 21- 75
4. Unilateral total knee arthroplasty at Colorado Joint Replacement
5. All…
Contacts