Doxycycline and Progestin Therapy for Chronic Endometritis(CE) in Patients With Recurrent Reproductive Failure(RRF)
Recruiting
N/A
Interventional Study
Chronic Endometritis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 20 – 45
- Sex
- Female
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 1,000 (estimated)
- Sponsor
- Fang Wang · Other
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About This Trial
A Prospective Randomized Controlled Trial, the goal of this clinical trial is to evaluate the efficacy and safety of doxycycline alone versus doxycycline plus medroxyprogesterone acetate (MPA) in women with chronic endometritis (CE), and to assess subsequent reproductive outcomes. Participants will be randomly assigned to one of two groups and will receive the assigned treatment. Participants will…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* women aged 20-45 years;
* plans to conceive within 12 months;
* chronic endometritis(CE) confirmed by endometrial CD138 immunohistochemistry (IHC);
* a diagnosis of recurrent reproductive failure(RRF);
* willingness to undergo hysteroscopy and endometrial biopsy;
* no contrain…
Contacts