No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 100
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
200 (estimated)
Sponsor
Cappagh National Orthopaedic Hospital · Other
Who this trial is looking for
This trial is looking for adults with painful knee osteoarthritis. Participants will receive either Arthrosamid or standard steroid treatment to see which is more effective.
Are You a Good Fit for This Trial?
Must not be takingCorticosteroidsHyaluronic acid
Rules you outRheumatoid arthritisGoutThrombocytopeniaCoagulopathyKnee joint infection
You may be able to join if
I am an adult
I have knee pain on one side
I have been diagnosed with knee osteoarthritis grades II-IV on x-ray or MRI
You may not be able to join if
I have an inflammatory condition
I have cancer
I have an acute infection
I am pregnant or breastfeeding
I have uncontrolled diabetes
I have other knee joint diseases
I have had knee surgery with a metallic implant
I have had a knee arthroscopy in the past 6 months
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
This study will be a randomised control trial of the use of intra-articular Arthrosamid® a novel intraarticular hydrogel vs. standard of care (steroid and local anaesthetic) for the non-operative management of knee osteoarthritis.
Trial Locations
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City
State
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Status
Eligibility Criteria
Inclusion Criteria:
* Adults
* Symptomatic single side knee pain.
* Patients with diagnosis of knee osteoarthritis radiographic Kellgren and Lawrence system OA grade II-III-IV on x ray or MRI.
Exclusion Criteria:
* Inflammatory conditions,
* Cancer,
* acute infection,
* pregnancy and breastfeedin…
Inclusion Criteria:
* Adults
* Symptomatic single side knee pain.
* Patients with diagnosis of knee osteoarthritis radiographic Kellgren and Lawrence system OA grade II-III-IV on x ray or MRI.
Exclusion Criteria:
* Inflammatory conditions,
* Cancer,
* acute infection,
* pregnancy and breastfeeding.
* Uncontrolled diabetes mellitus,
* Joint diseases in the knee, such as rheumatoid arthritis or gout, history of knee surgery with metallic implant.
* If patient has undergone knee arthroscopy in past 6 months.
* Intra-articular injection of corticosteroids during the previous 3 months, intra-articular injection of other drugs, such as hyaluronic acid over the previous 1 year.
* Contraindications for intra-articular injection, such as thrombocytopenia, coagulopathy, articular infection of knee, impairment of immunity.
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