Liquid Biopsy in Paraneoplastic Neurological Syndromes
Recruiting
Observational Study
Paraneoplastic Neurological Syndromes
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 60 (estimated)
- Sponsor
- Heinrich-Heine University, Duesseldorf · Other
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About This Trial
The main objective of the study is to assess whether circulating tumor cells (CTCs) can be detected in the peripheral blood of patients with paraneoplastic neurological syndromes (PNS) by diagnostic leukapheresis (DLA) combined with the CELLSEARCH® System during clinical routine workup. If CTCs can be identified, a detailed molecular genetic analysis will be performed to characterize mutations in …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients with paraneoplastic neurological syndromes (PNS) and high- or intermediate-risk or GAD65-antibodies or
* Patients with peripheral tumors without PNS
Exclusion Criteria:
* Age below 18 years at the time of inclusion.
* Any mental condition impairing the capacity to p…
Contacts