Aerobic Exercise and Brain Stimulation for Older Adults
A Novel Multi-Modal Approach to Promote Functional Outcomes in Cognitively Frail Older Adults
Recruiting
N/A
Interventional Study
Frailty at Older Adults
Mild Cognitive Impairment
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 60 – 90
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 45 (estimated)
- Sponsor
- The Hong Kong Polytechnic University · Other
Who this trial is looking for
This trial is looking for older adults aged 60 to 90 who have mild cognitive impairment and are physically frail. Participants will engage in aerobic exercise along with a type of brain stimulation to see how it affects their thinking and mobility.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 60 and 90 years old.
- I scored less than 9 on the SPPB test.
- I scored more than 18 on the MoCA test.
- I scored more than 9 on the PFFS test.
- I live in the community.
- I can walk up to four meters with or without help.
- I can give written consent.
- I understand Cantonese and/or English.
You may not be able to join if
- I have MRI contraindications.
- I have aerobic exercise contraindications.
- I have transcranial magnetic stimulation contraindications.
- I have been diagnosed with dementia or other neurodegenerative conditions.
- I live in a nursing home or care facility.
- I am taking medications that could affect my cognitive and physical function.
- I have a history of falls due to loss of consciousness.
- I have cancer and am undergoing radiation therapy.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
The goal of this clinical trial is to explore the effects of intermittent theta burst stimulation (iTBS) primed with theta burst stimulation (cTBS), on top of aerobic exercise, on cognitive function, mobility, and brain activity in older adults with cognitive frailty. Understanding these effects will help us develop intervention models that benefit cognitively frail older adults. The main question…
Trial Locations
Loading…
Loading trial locations…
Eligibility Criteria
Inclusion Criteria:
1. be between 60 and 90 years old;
2. scored \< 9/12 on the SPPB;
3. scored \>18/30 on the MoCA;
4. scored \>9/42 on the PFFS;
5. lived in the community;
6. be able to ambulate up to four meters with or without assistive devices;
7. be able to provide written informed consent on…
Contacts