Integrating Digital Phenotypes and AI-Driven Cognitive-Behavioral Therapy: Advancing Precision Medicine in Depression Through Digital Medicine
Recruiting
N/AInterventional Study
Depression - Major Depressive Disorder
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 75
Sex
Any
Study type
Interventional
Purpose
Supportive Care
Participants needed
100 (estimated)
Sponsor
National Science and Technology Council, Taiwan · Government
Who this trial is looking for
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This project aims to integrate digital phenotyping and AI-driven iCBT into a comprehensive platform for MDD diagnosis and treatment in Taiwan. The study will explore dynamic, real-time behavioral and physiological markers to refine diagnostic classifications and optimize personalized therapeutic strategies.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* (1) Aged 18-75 years
* Diagnosis of major depressive disorder disorder (Based on Diagnostic Statistical Manual 5)
* 21-item Hamilton Depression Scale (HAMD21)\>17
* No changes in current psychiatric treatment for depression (e.g., no treatment, antidepressant medication, psych…
Inclusion Criteria:
* (1) Aged 18-75 years
* Diagnosis of major depressive disorder disorder (Based on Diagnostic Statistical Manual 5)
* 21-item Hamilton Depression Scale (HAMD21)\>17
* No changes in current psychiatric treatment for depression (e.g., no treatment, antidepressant medication, psychotherapy, or non-invasive brain stimulation) within the past four weeks, and
* Full competency to understand the study details and provide written informed consent
Exclusion Criteria:
* Scores of 5 ( Markedly ill), 6,(Severely ill), and 7 (Among the most extremely ill) according to the Clinical Global Impression Scale-Severity (CGI-S)
* Psychotic disorders, bipolar affective disorder, a substance use disorders in the past 6 months, active suicidal or homicidal ideation (per assessment or HAMD\>3)
* Unstable or active medical illness.
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