Trunk Inclination, Positive End-expiratory Pressure, and Lung Recruitability
Recruiting
Observational Study
Acute Respiratory Distress Syndrome (ARDS)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 40 (estimated)
- Sponsor
- Zhongda Hospital · Other
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About This Trial
This multicenter, physiological, observational study hypothesizes that in moderate to severe ARDS, trunk inclination unloads the chest wall, but its impact on lung mechanics depends on PEEP levels and lung recruitability.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Intubated moderate and severe ARDS according to the Berlin definition (PaO2/FiO2 ratio \<= 200 mmHg)
* Under continuous sedation with or without paralysis
Exclusion Criteria:
* Age \<18 years
* Bronchopleural fistula
* Pure COPD exacerbation
* Contraindication to EIT monitor…
Contacts