Effect of Intercostal Nerve Block With Liposomal Bupivacaine on Quality of Recovery in VATS Partial Pneumonectomy
Recruiting
Phase 4
Interventional Study
Pulmonary Nodule
Liposomal Bupivacaine
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 96 (estimated)
- Sponsor
- Sanming First Hospital · Other
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About This Trial
Video-assisted thoracoscopic surgery (VATS) is a minimally invasive approach for partial pneumonectomy, but postoperative pain remains a major challenge affecting recovery. Intercostal nerve block (ICNB) with conventional local anesthetics provides limited duration of analgesia, often insufficient to cover the peak pain period after surgery. Liposomal bupivacaine is a long-acting formulation desig…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients scheduled for thoracic surgery under general anesthesia via thoracoscopic approach;
* Age 18-65 years;
* Classified as Grade I-II by the American Society of Anesthesiologists (ASA).
Exclusion Criteria:
* History of local anesthetic allergy.
* Chronic opioid users.
*…
Contacts