GRAfT 2.0. A Multimodal Prospective Approach to Define the Mechanisms and Clinical Features of Acute and Chronic Rejection in Lung Transplantation

Recruiting Observational Study
Lung Transplant End Stage Lung Disease Rejection
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 75
Sex
Any
Study type
Observational
Participants needed
100 (estimated)
Sponsor
National Heart, Lung, and Blood Institute (NHLBI) · NIH
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About This Trial
Background: Lung transplants can save lives, but the procedure has risks. Some people develop donor-specific antibodies (DSA) after the procedure-that is, their bodies create proteins that treat the new lungs as foreign and mount an immune response against them. This is called rejection. But not everyone who has a transplant develops DSA, and not everyone who has DSA develops rejection. Researche…
Trial Locations
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Eligibility Criteria
* INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all of the following criteria: 1. Stated willingness to comply with study procedures and availability for the duration of the study. 2. Male or female, aged 18 - 75 years of age. 3. Have progressive…
Contacts

Andrew G Keel, C.R.N.P.

(301) 648-5674

andrew.keel@nih.gov

CONTACT

Muhtadi H Alnababteh, M.D.

(301) 827-3272

muhtadi.alnababteh@nih.gov

CONTACT