A Single Dose, Phase 1 Study of JADE101 in Healthy Japanese and Chinese Participants
Recruiting
Phase 1Interventional Study
Healthy Volunteers (HV)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 55
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Basic Science
Participants needed
40 (estimated)
Sponsor
Jade Biosciences, Inc. · Industry
Who this trial is looking for
This trial is looking for healthy Japanese and Chinese adults aged 18 to 55. Participants will take a single dose of the drug JADE101 and undergo various assessments to check safety and effects.
Are You a Good Fit for This Trial?
You may be able to join if
I am a healthy male or female aged 18 to 55.
I was born in Japan or China.
I weigh between 40 and 100 kg.
My BMI is between 18.0 and 32.0.
I can follow study requirements and visits.
I can meet contraceptive and lifestyle guidelines.
You may not be able to join if
I have harmful alcohol use.
I have smoked or vaped heavily in the last 2 years.
I have a history of drug abuse.
I am nursing, pregnant, or planning to get pregnant.
I have a history of significant disease.
I have a known immunodeficiency disorder.
I have a history of serious allergic reactions.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
This is a Phase 1 study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of a single dose of JADE101 in healthy Japanese and Chinese participants.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Healthy male or female participants 18-55 years of age, inclusive
2. First-generation Japanese or Chinese participants born in Japan/China
3. A body weight between 40-100 kg and a body mass index (BMI) between 18.0 - 32.0 kg/m2 (all inclusive) at screening
4. Willing and able…
Inclusion Criteria:
1. Healthy male or female participants 18-55 years of age, inclusive
2. First-generation Japanese or Chinese participants born in Japan/China
3. A body weight between 40-100 kg and a body mass index (BMI) between 18.0 - 32.0 kg/m2 (all inclusive) at screening
4. Willing and able to comply with the study site stay, scheduled visits, and study procedures
5. Willing and able to comply with contraceptive and lifestyle requirements from admission through the end of the study
Exclusion Criteria:
1. Harmful alcohol use
2. Smoking/vaping or heavy tobacco use within 2 years prior to screening
3. Known history of abuse of illicit drugs
4. Nursing, lactating or pregnant, or who have plans to become pregnant during the study
5. Known history of clinically significant disease
6. Known history of immunodeficiency disorder
7. History of clinically significant allergic reactions or hypersensitivity
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