Brepocitinib for Lichen Planopilaris

A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris

Recruiting Phase 2 Phase 3 Interventional Study
Lichen Planopilaris
Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2/3
Study type
Interventional
Purpose
Treatment
Participants needed
342 (estimated)
Sponsor
Priovant Therapeutics, Inc. · Industry
Who this trial is looking for

This trial is looking for adults with a condition called lichen planopilaris. Participants will take an oral medication called brepocitinib to see how safe and effective it is for their symptoms.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am at least 18 years old
  • I weigh more than 40 kg but less than 130 kg
  • My body mass index (BMI) is 45 or less
  • I have had a biopsy that confirms I have lichen planopilaris
  • I have active and symptomatic lichen planopilaris

You may not be able to join if

  • I have a history of a lymphoproliferative disorder
  • I have an active cancer or had cancer in the last 5 years
  • I am at high risk for blood clots or heart disease
  • I am at high risk for shingles (herpes zoster)
  • I have an active or recent infection

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial

This study will evaluate the clinical safety and efficacy of oral brepocitinib in participants with lichen planopilaris

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Age ≥ 18 years 2. Scalp biopsy consistent with LPP 3. Active and symptomatic LPP at screening and baseline- 4. Weight \> 40 kg to \< 130 kg with BMI ≤ 45 kg/m2 Exclusion Criteria: 1. History of: Lymphoproliferative disorder; Active malignancy; History of cancer within 5 yea…
Contacts

Clinical Trial Administrator

(212) 634-9743

clinicaltrials@priovant.com

CONTACT