Dental Cleaning to Prevent Chronic Graft-Versus-Host Disease
Recruiting
N/A
Interventional Study
Chronic Graft Versus Host Disease
Acute Graft Versus Host Disease
Hematopoietic and Lymphatic System Neoplasm
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 45 (estimated)
- Sponsor
- Fred Hutchinson Cancer Center · Other
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About This Trial
This clinical trial evaluates the feasibility and effectiveness of a post-transplant dental cleaning for the prevention of chronic graft versus host disease (GVHD) in patients undergoing an allogeneic hematopoietic cell transplant (HCT). HCT is the only curative treatment for some types of blood cancer. Unfortunately, this approach can lead to the development of GVHD, which is a disease caused whe…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age ≥ 18 years old
* T-replete allogeneic hematopoietic cell transplantation for any indication. History of prior transplantation is allowed. Any conditioning regimen is allowed
* One of the following HCT donor types:
* 9/10 or 10/10 human leukocyte antigen (HLA)-matched un…
Contacts