Antihistamine for Prevention of HTR After Blood Primed CPB
Recruiting
Phase 4
Interventional Study
Blood Transfusion Associated Adverse Reactions
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 1 – 7
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 40 (estimated)
- Sponsor
- Kasr El Aini Hospital · Other
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About This Trial
This study will be a randomized, double-blinded, placebo-controlled study conducted at a university hospital. Forty children undergoing elective repair of a congenital heart defect will be included. The patients will be randomly allocated (20 patients per group) to receive a single intravenous dose of combined chlorpheniramine or normal saline immediately after separation from CPB, before protamin…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Acyanotic congenital heart disease.
* Age :1 -7 years.
* Genre: both.
Exclusion Criteria:
* Redo patient.
* History of allergy to antihistamines.
* Bleeding disorders with INR \> 1.5 and/or platelets \< 50,000.
* Emergency procedure.
Contacts
No contact information available.