A Multimodal Prospective Cohort Study of Parkinsonism
Recruiting
Observational Study
Parkinsonism
REM Sleep Behavior Disorder
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 31 – 79
- Sex
- Any
- Study type
- Observational
- Participants needed
- 640 (estimated)
- Sponsor
- Ruijin Hospital · Other
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About This Trial
This is a single-center, prospective, observational cohort study designed to investigate the progression and differential diagnosis of Parkinsonism using a multimodal approach. The study plans to enroll 400 patients with Parkinsonism, 120 patients with rapid eye movement sleep behavior disorder, and 120 healthy controls, with follow-up for 5 years.
Assessments will include neuroimaging, clinical …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
For participants with rapid eye movement sleep behavior disorder:
* Meets the diagnostic criteria for rapid eye movement sleep behavior disorder established by the American Academy of Sleep Medicine
* Chinese citizen
* Age \>30 years and \<80 years
* Able to understand the stud…
Contacts