Mechanochemical Ablation Versus Ultrasound-Guided Foam Sclerotherapy of the Great Saphenous Vein

Recruiting Phase 4 Interventional Study
Varicose Veins of Leg With Long Saphenous Vein Distribution Varicose Veins of Lower Limb
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
50 (estimated)
Sponsor
Antonio Eduardo Zerati · Other
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About This Trial
This study compares two minimally invasive treatments for varicose veins in the legs, specifically the great saphenous vein. Varicose veins can cause symptoms such as leg pain, swelling, and skin changes. One commonly used treatment is foam sclerotherapy, where a special foam is injected into the vein to close it. This method is simple and allows patients to return quickly to their daily activiti…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * CEAP Classification C2, 3 or 4 * Insufficient great saphenous vein measuring 6-12 mm in the mid-thigh on Doppler ultrasound. Exclusion Criteria: * Allergy to sclerosing substances * Deep venous thrombosis, stroke, or pulmonary embolism * Local or generalized infection at the…
Contacts

Antonio Zerati, PhD

+5511996354925

a.zerati@fm.usp.br

CONTACT