No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
0 Days – 45
Sex
Any
Study type
Observational
Participants needed
240 (estimated)
Sponsor
Far Eastern Memorial Hospital · Other
Who this trial is looking for
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This prospective cohort study examines the relationship between maternal methyl-nutrient status during pregnancy and offspring neurodevelopment. It integrates maternal dietary, biomarker, genetic, and microbiome data and follows children up to 24 months.
Trial Locations
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Eligibility Criteria
Inclusion Criteria for Pregnant Women
* Aged 20-45 years
* Singleton pregnancy
* Receiving routine prenatal care at the study site and planning to deliver at Far Eastern Memorial Hospital
Exclusion Criteria for Pregnant Women
* Diagnosed with major chronic diseases, including renal disease (defin…
Inclusion Criteria for Pregnant Women
* Aged 20-45 years
* Singleton pregnancy
* Receiving routine prenatal care at the study site and planning to deliver at Far Eastern Memorial Hospital
Exclusion Criteria for Pregnant Women
* Diagnosed with major chronic diseases, including renal disease (defined as chronic kidney disease stage 3 or above or history of renal transplantation), liver disease (defined as liver cirrhosis or history of liver transplantation), or malignancy
* Alcohol consumption during pregnancy
* Diagnosed with eating disorders or psychiatric conditions that may impair the assessment of nutritional status
Inclusion Criteria for Newborns
● Newborns delivered by mothers who participate in this study
Exclusion Criteria for Newborns
* Diagnosed with congenital anomalies, epilepsy, or severe brain injury
* Inability to complete neurodevelopmental assessments at 6 months, 1 year, and 2 years of age at the study site
* Infants whose mothers are diagnosed with eating disorders or psychiatric conditions that may impair the assessment of nutritional status
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