Dexmedetomidine vs Ketamine for Pain Relief in Surgery

Adding Dexmedetomidine Versus Ketamine to Bupivacaine in Fluoroscopy Guided Caudal Analgesia for Lumbosacral Surgeries

Recruiting Phase 3 Interventional Study
Perioperative Analgesia
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
21 – 60
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Other
Participants needed
72 (estimated)
Sponsor
Ain Shams University · Other
Who this trial is looking for

This trial is looking for people who are having lumbosacral surgery while under general anesthesia. Participants will receive either dexmedetomidine or ketamine along with bupivacaine for pain relief.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am between 21 and 60 years old.
  • I can be male or female.
  • I am healthy or have mild medical issues (ASA Class I or II).
  • I am scheduled for lumbosacral surgery under general anesthesia.

You may not be able to join if

  • I cannot give written consent or have serious memory issues.
  • I am allergic to the medications used in the study.
  • I have conditions that prevent me from receiving regional anesthesia.
  • I have recently taken pain medication or abused drugs.
  • I am pregnant or breastfeeding.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial

This study will evaluate the effect of adding dexmedetomidine to bupivacaine compared to ketamine in the caudal block on perioperative analgesia in patients undergoing lumbosacral surgeries under general anesthesia.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age 21-60 years. * Sex: Both sexes. * American Society of Anesthesiologists (ASA) Physical Status Class-I and II. * Scheduled for lumbosacral surgery under General Anesthesia. Exclusion Criteria: * Declining to give written informed consent or patients with significant cogni…
Contacts

Salma Ayman Abdulazeem, MSc

+201285665828

Salmaaymen0103389@med.asu.edu.eg

CONTACT