CUPID: Couples Support for HIV Prevention in Uganda
Improving Choice And Use Of Biomedical HIV Prevention For Women In Uganda: A Couples-based Approach
Recruiting
N/AInterventional Study
HIV
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
1,424 (estimated)
Sponsor
RTI International · Other
Who this trial is looking for
This trial is looking for women aged 18 and older to participate in a program that encourages couples to support women's choices about HIV prevention. Participants will engage in discussions and complete study procedures related to HIV prevention practices.
Are You a Good Fit for This Trial?
You may be able to join if
I am 18 years or older.
I can provide written consent.
I speak English or the local language.
I attend a PrEP follow-up visit.
I am willing to participate in discussions.
You may not be able to join if
I have a condition that prevents me from giving informed consent.
I am aged 15-17 years.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
This research will evaluate the effectiveness and implementation of a couples shared decision-making intervention, CUPID (Couples United in HIV Prevention Informed Decisions), delivered in community and clinic settings to support women's pre-exposure prophylaxis (PrEP) choice and use through male partner support and shared decision-making. Through a partnership with Ministry of Health clinics alre…
This research will evaluate the effectiveness and implementation of a couples shared decision-making intervention, CUPID (Couples United in HIV Prevention Informed Decisions), delivered in community and clinic settings to support women's pre-exposure prophylaxis (PrEP) choice and use through male partner support and shared decision-making. Through a partnership with Ministry of Health clinics already providing choices for PrEP in Uganda, the investigators will evaluate whether CUPID is effective in increasing PrEP uptake, persistence, and use among Ugandan women and assess implementation outcomes to determine whether it is acceptable and feasible to implement. If successful, CUPID will offer a community-based strategy for engaging male partners to support PrEP choice and improve HIV prevention among women and provide a scalable and sustainable intervention that will contribute to a more comprehensive approach to HIV prevention.
Trial Locations
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City
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Status
Eligibility Criteria
Inclusion Criteria:
All Aims:
1. Able and willing to provide written informed consent
2. Fluent in English or the dominant language spoken in the health facility's region.
Aim 1:
1. Age ≥18 years
2. Meets one of the following criteria:
1. Performs tasks related to PrEP outreach and/or delive…
Inclusion Criteria:
All Aims:
1. Able and willing to provide written informed consent
2. Fluent in English or the dominant language spoken in the health facility's region.
Aim 1:
1. Age ≥18 years
2. Meets one of the following criteria:
1. Performs tasks related to PrEP outreach and/or delivery in former CATALYST study areas. This may include clinic and non-clinic positions.
2. Is a member of one of the three regional CATALYST CABs
3. Willing to participate in a focus group discussion
Aim 2:
1. Aged 18 years or older
2. Attending a PrEP follow-up visit
3. Able and willing to complete all study procedures.
Aim 3:
1. Age ≥18 years
2. Meets one of the following criteria:
1. CUPID couples' decision tool user
2. A CUPID intervention provider (member of a CHT or other PrEP Provider)
3. A provider offering PrEP choice through a health facility where CUPID is implemented
4. MOH or District Health Official
3. Willing to complete a questionnaire and participate in a qualitative interview (individual or dyadic)
Exclusion Criteria:
All Aims: Participants will be excluded who have any condition that, in the opinion of the MPI or designee, would preclude informed consent, make study participation unsafe, complicate interpretation of study outcome data, or otherwise interfere with achieving the study objectives.
Aim 2:
Exclusion criteria: Participants aged 15-17 years
Contacts
No contact information available.
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