Spasticity in SCI Following Acute Intermittent Hypoxia

Recruiting N/A Interventional Study
Spinal Cord Injuries (SCI)
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Diagnostic
Participants needed
10 (estimated)
Sponsor
Zev Rymer · Other
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About This Trial

This study aims to observe the effects of administration of a breathing intervention (Acute Intermittent Hypoxia (AIH)) on spasticity (tightness) in individuals with incomplete Spinal Cord Injury. It is hypothesized that hypoxia will decrease the reflex threshold of the biceps brachii, indicating an increase in spasticity following the AIH.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age \>= 18 * Non-progressive spinal Cord injury at least 6 months prior * Level of injury between C1-C8 * ISNCSCI ASIA classification C or D * Measurable Spasticity Exclusion Criteria: * Pre-existing hypoxic pulmonary disease * Positive Covid-Pneumonia diagnosis within 1 yea…
Contacts

William Z Rymer, MD, PhD

312-238-3919

w-rymer@northwestern.edu

CONTACT

Alexander Barry, MS

312-238-1435

abarry@sralab.org

CONTACT