Alternative Splicing Based Prediction of Chemotherapy Response in Gastric Cancer
Recruiting
Observational Study
Gastric Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 329 (estimated)
- Sponsor
- City of Hope Medical Center · Other
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About This Trial
This study aims to develop a model to predict response to chemotherapy in gastric cancer using RNA splicing information from tumor tissue. By analyzing genetic patterns and applying machine learning, the study seeks to identify patients who are less likely to benefit from treatment, helping guide clinical decision-making.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Pathologically confirmed stage II or III gastric cancer
* Underwent curative surgical resection
* Received 5-FU-based adjuvant chemotherapy
* Availability of tumor tissue samples for analysis
Exclusion Criteria:
* History of other malignancies
* Inadequate or poor-quality ti…
Contacts