Molecular Profiling for Risk Stratification in Appendiceal Cancer
Recruiting
Observational Study
Appendiceal Cancer
Appendiceal Adenocarcinoma
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 400 (estimated)
- Sponsor
- City of Hope Medical Center · Other
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About This Trial
This study investigates integrated epigenetic and epitranscriptomic features of appendiceal cancer using archived tumor tissue specimens from the same patient cohort. The study includes DNA methylation profiling and m6A epitranscriptomic profiling to define molecular subtypes, evaluate associations with clinicopathologic features, and develop molecular risk scores for prognostic stratification. Th…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients with histologically confirmed appendiceal adenocarcinoma or appendiceal cancer.
* Availability of archived tumor tissue suitable for molecular profiling.
* Availability of tissue for DNA methylation profiling, m6A epitranscriptomic profiling, or both.
* Availability o…
Contacts