Netarsudil for Glaucoma and Ocular Hypertension
Imaging the Effects of Netarsudil (Rhopressa) on the Trabecular Meshwork in Glaucoma and Ocular Hypertension
Recruiting
Phase 4
Interventional Study
Glaucoma
Ocular Hypertension
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 50 (estimated)
- Sponsor
- Indiana University · Other
Who this trial is looking for
This trial is looking for adults with glaucoma or high eye pressure. Participants will receive either netarsudil eye drops or a placebo and will undergo eye imaging tests over about two weeks.
Are You a Good Fit for This Trial?
You may be able to join if
- I am 18 years or older
- I have been diagnosed with ocular hypertension or open-angle glaucoma
- I had an eye exam within the past year
- I have visual field test results that show glaucoma
- My best-corrected vision is 20/100 or better
- My eye angle is open as confirmed by tests
- My eye pressure is between 18 and 34 mmHg
You may not be able to join if
- I am intolerant to netarsudil eye drops
- I have corneal scarring or an active eye disease
- I cannot tolerate gonioscopy procedures
- I am a woman of childbearing potential not using effective contraception
- I have a condition that may increase my risk or interfere with the study
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
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About This Trial
This study evaluates the effects of netarsudil (Rhopressa) on the trabecular meshwork in subjects with ocular hypertension or open-angle glaucoma. Participants will be randomized to receive either netarsudil or placebo (artificial tears). High-resolution imaging using adaptive optics gonioscopy, anterior segment optical coherence tomography (AS-OCT), and OCT gonioscopy will be performed at baselin…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adults aged 18 years or older
* Diagnosis of ocular hypertension or open-angle glaucoma
* Eye examination within the past year
* For glaucoma subjects: structural (optic nerve and/or retinal nerve fiber layer) and functional (visual field) findings consistent with glaucoma
* B…
Contacts