Local And Systemic Macrophage Activation in Coronary and Peripheral Artery Disease
Recruiting
N/A
Interventional Study
Stable Coronary Artery Disease
Acute Coronary Syndromes
Critical Limb Ischemia
Intermittent Claudication
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 60 (estimated)
- Sponsor
- Maria Cecilia Hospital · Other
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About This Trial
Numerous clinical studies have highlighted the role of macrophages in the destabilization of coronary lesions; however, there is limited literature on the relationship between circulating monocytes and intraplaque macrophages.
This study aims to evaluate and compare the presence of macrophages and their subsequent activation within coronary and peripheral atherosclerotic lesions, and to correlate…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients with chronic coronary artery disease;
* Patients with no-ST elevation acute coronary syndrome;
* Patients with chronic claudication (Rutherford II-III)
* Patients with critical limb ischemia (Rutherford IV-V).
Exclusion Criteria:
* Severe renal dysfunction
* Severe …
Contacts