Association Between Irrigation Fluid Absorption and Perioperative cfDNA Dynamics After TURBT

Recruiting Observational Study
Bladder (Urothelial, Transitional Cell) Cancer Bladder Cancer Recurrence Progression of Bladder Cancer Transurethral Resection of Bladder Tumor Urothelial Carcinoma of the Bladder
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
150 (estimated)
Sponsor
Zhiping Wang · Other
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About This Trial
This prospective observational cohort study aims to evaluate the association between intraoperative irrigation fluid absorption and perioperative cell-free DNA (cfDNA) dynamics in patients undergoing transurethral resection of bladder tumor (TURBT). Eligible patients with suspected or confirmed bladder cancer scheduled for TURBT will be enrolled. Intraoperative irrigation fluid absorption volume w…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Age 18 years or older. 2. Suspected or histologically confirmed urothelial carcinoma of the bladder. 3. Scheduled to undergo TURBT. 4. Availability of sufficient peripheral blood samples for cfDNA extraction and mutation analysis. 5. Availability of complete clinicopathologic…
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