Dual-Target CAR-NK Cells in Recurrent or Refractory Epithelial Ovarian Cancer

Recruiting Phase 1 Phase 2 Interventional Study
Epithelial Ovarian Cancer Epithelial Ovarian Cancer, Fallopian Tube or Peritoneum
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 75
Sex
Female
Trial phase
Phase 1/2
Study type
Interventional
Purpose
Treatment
Participants needed
42 (estimated)
Sponsor
Beijing Biotech · Industry
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About This Trial
This study evaluates the safety, tolerability, and preliminary anti-tumor activity of EB-DUALNK, a dual-target chimeric antigen receptor natural killer (CAR-NK) cell therapy, in adults with recurrent or refractory epithelial ovarian cancer. Candidates for targeting include GD2, MUC1, PSMA, and mesothelin. After baseline biomarker assessment (tumor antigen expression), the program will select the m…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age 18-75 years; able to provide written informed consent. * Histologically confirmed epithelial ovarian, fallopian tube, or primary peritoneal carcinoma that is recurrent or refractory after standard therapy (at least 2 prior systemic regimens), with measurable disease per RE…
Contacts

shan S Lu, Phd

+86 13076790030

Seni-Lu@beijing-biotech.com

CONTACT